1 NMDAR antagonist action in
نویسندگان
چکیده
Correspondence: John E. Lisman 9 Department of Biology and Volen Center for Complex Systems, 10 Brandeis University, MS 008 11 415 South Street, 12 Waltham, Massachusetts 02454 13 Email: [email protected] 14 Tel: (781) 736-3145 15 Fax: (781) 736-3107 16 17 Numbers of pages: 23 18 Number of words in the Abstract: 242 19 Number of words in the Introduction: 722 20 Number of words in the Discussion: 1758 21 Number of figures: 6 22 Number of tables: 0 23 Number of supplementary material: 0 24 25 26
منابع مشابه
Inhibition of NR2B-Containing N-methyl-D-Aspartate Receptors (NMDARs) in Experimental Autoimmune Encephalomyelitis, a Model of Multiple Sclerosis
Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been suggested for neuroprotection, but selective antagonisation of the NR2B subtype of these receptors, a subtype believed to play a more pivotal ...
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Neurodegeneration is the pathophysiological basis for permanent neurological disabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic approach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been suggested for neuroprotection, but selective antagonisation of the NR2B subtype of these receptors, a subtype believed to play a more pivotal ...
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Zhang Y, Yoshida T, Katz DB, Lisman JE. NMDAR antagonist action in thalamus imposes delta oscillations on the hippocampus. J Neurophysiol 107: 3181–3189, 2012. First published March 14, 2012; doi:10.1152/jn.00072.2012.—Work on schizophrenia demonstrates the involvement of the hippocampus in the disease and points specifically to hyperactivity of CA1. Many symptoms of schizophrenia can be mimick...
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